Publikationen

2026


Colonic spatial single-cell proteomics and murine models link mitochondrial dysfunction to dimeric IgA-secreting plasma cell deficiency in Crohn's disease., Nature Communications , 2026.
DOI:10.1038/s41467-026-69069-w

2025


Transcriptome-Wide Analysis and Experimental Validation from FFPE Tissue Identifies Stage-Specific Gene Expression Profiles Differentiating Adenoma, Carcinoma In-Situ and Adenocarcinoma in Colorectal Cancer Progression., International Journal of Molecular Sciences , 2025.
DOI:10.3390/ijms26094194

Centrifugal Microfluidic Lateral Flow Assay Enables High Sensitivity Interleukin-6 Detection and Ultrafast Readout of Elevated Analyte Levels., Analytical Chemistry , 2025.
DOI:10.1021/acs.analchem.5c00413

Coupling Immunoprecipitation with Multiplexed Digital PCR for Cell-Free DNA Methylation Detection in Small Plasma Volumes of Early-Onset Colorectal Cancer., Analytical Chemistry , 2025.
DOI:10.1021/acs.analchem.5c01361

Low-coverage whole genome sequencing of cell-free DNA to predict and track immunotherapy response in advanced non-small cell lung cancer., Journal of Experimental & Clinical Cancer Research , 2025.
DOI:10.1186/s13046-025-03348-0

Fostering the implementation of liquid biopsy in clinical practice: meeting report 2024 of the European Liquid Biopsy Society (ELBS)., Journal of Experimental & Clinical Cancer Research , 2025.
DOI:10.1186/s13046-025-03398-4

Impact of Single Freeze-Thaw Cycles on Serum Protein Stability: Implications for Clinical Biomarker Validation Using Mass Spectrometry., 2025.
DOI:10.1101/2025.04.09.647925

2024


Integration of Oncological Data into openEHR: A Path Towards Improved Cancer Care and Research., Studies in Health Technology and Informatics , 2024.
DOI:10.3233/SHTI240655

Unlocking Potential: Personalized Lifestyle Therapy for Type 2 Diabetes Through a Predictive Algorithm-Driven Digital Therapeutic., Journal of Diabetes Science and Technology , 2024.
DOI:10.1177/19322968241266821

Complete cancer prevalence in Europe in 2020 by disease duration and country (EUROCARE-6): a population-based study., The Lancet Oncology , 2024.
DOI:10.1016/S1470-2045(23)00646-0

Survival of European adolescents and young adults diagnosed with cancer in 2010-2014., European Journal of Cancer , 2024.
DOI:10.1016/j.ejca.2024.113558

Differences in survival and recurrence of colorectal cancer by stage across population-based European registries., International Journal of Cancer , 2024.
DOI:10.1002/ijc.34944

Transcriptome Profiling Associated with CARD11 Overexpression in Colorectal Cancer Implicates a Potential Role for Tumor Immune Microenvironment and Cancer Pathways Modulation via NF-kappaB., International Journal of Molecular Sciences , 2024.
DOI:10.3390/ijms251910367

2023


Panomics reveals patient individuality as the major driver of colorectal cancer progression, Journal of Translational Medicine , 2023.
DOI:10.1186/s12967-022-03855-0

Estimating complete cancer prevalence in Europe: validity of alternative vs standard completeness indexes., Frontiers in Oncology , 2023.
DOI:10.3389/fonc.2023.1114701

An overview and a roadmap for artificial intelligence in hematology and oncology., Journal of Cancer Research and Clinical Oncology , 2023.
DOI:10.1007/s00432-023-04667-5

Population-Based Clinical Cancer Registration in Germany., Cancers (Basel) , 2023.
DOI:10.3390/cancers15153934

Temporal trends in age- and stage-specific incidence of colorectal adenocarcinomas in Germany., BMC Cancer , 2023.
DOI:10.1186/s12885-023-11660-1

Nanobead handling on a centrifugal microfluidic LabDisk for automated extraction of cell-free circulating DNA with high recovery rates., Analyst , 2023.
DOI:10.1039/d2an01820a

Gut Microbiome Analysis for Personalized Nutrition: The State of Science., Molecular Nutrition & Food Research , 2023.
DOI:10.1002/mnfr.202200476

Immunohistochemical Expression Analysis of Caldesmon Isoforms in Colorectal Carcinoma Reveals Interesting Correlations with Tumor Characteristics., International Journal of Molecular Sciences , 2023.
DOI:10.3390/ijms24032275

Development of Highly Sensitive Digital Droplet PCR for Detection of cKIT Mutations in Circulating Free DNA That Mediate Resistance to TKI Treatment for Gastrointestinal Stromal Tumor (GIST)., International Journal of Molecular Sciences , 2023.
DOI:10.3390/ijms24065411

Uncovering the relationship between gut microbial dysbiosis, metabolomics, and dietary intake in type 2 diabetes mellitus and in healthy volunteers: a multi-omics analysis., Scientific reports , 2023.
DOI:10.1038/s41598-023-45066-7

Colorectal Cancer Survival in German-Danish Border Regions-A Registry-Based Cohort Study., Cancers (Basel) , 2023.
DOI:10.3390/cancers15184474

Small intestine vs. colon ecology and physiology: Why it matters in probiotic administration., Cell Reports. Medicine , 2023.
DOI:10.1016/j.xcrm.2023.101190